Resolution Threshold of Current Molecular Epidemiology of Diphtheria

نویسنده

  • Igor Mokrousov
چکیده

Emerging Infectious Diseases • www.cdc.gov/eid • Vol. 20, No. 11, November 2014 1937 Author affiliations: Public Health England, Colindale, London, UK (M.A. Chattaway, C. Jenkins, H. Ciesielczuk, Martin Day, V. DoNascimento, Michaela Day, J. Threlfall, N. Woodford, J. Wain); Hospital Universitario Ramón y Cajal, Madrid, Spain (I. Rodríguez); University of East Anglia, Norfolk, UK (J. Wain); Federal Institute for Risk Assessment, Berlin, Germany (I. Rodríguez, B. Guerra, R. Helmuth); Central Veterinary Institute of Wageningen, Lelystad, the Netherlands (A. van Essen-Zandbergen, C. Dierikx, D. Mevius); Friedrich-Loeffler-Institut, Neustadt-Mariensee, Germany (A.-K. Schink, K. Kadlec, S. Schwarz); and Animal Health and Veterinary Laboratories Agency, Weybridge, UK (G. Wu, M.J. Woodward, N. Coldham)

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Impact of vaccination on epidemiology of diphtheria and pertussis

Whooping cough and diphtheria are vaccine preventable diseases. Diphtheria, due to Corynebacterium diphtheriae or Corynebactium ulcerans, two Gram positive bacteria, is a serious upper respiratory tract disease with high morbidity and mortality rates. Vaccination, via an acellular vaccine composed only of purified, detoxified diphtheria toxin, has significantly reduced the incidence of the dise...

متن کامل

Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis—General Aspects

V. A. de. C. Azevedo Departmento de Biologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil Abstract Corynebacterium diphtheriae, Corynebacterium ulcerans and Corynebacterium pseudotuberculosis are potentially diphtheria toxin-producing microorganisms related to different infectious processes involving both human and animal hosts. This chapte...

متن کامل

Preparation and in-vitro evaluation of sodium alginate microspheres containing diphtheria toxoid as new vaccine delivery

  During last two decades, polysaccharides such as alginate (Alg) alone and in combination with other biopolymers are widely used in vaccine and drug delivery systems. The aim of the present work was to investigate the potential utility of microparticles made of alginate (Alg) as new vehicles for improving nasal vaccine delivery. For this purpose, diphtheria toxoid (DT) was chosen as a model an...

متن کامل

Immunogenicity of a Triple Diphtheria-Tetanus-Whole Cell Pertussis Vaccine in Iranian Preschool Children

Background: Immunization against diphtheria, tetanus and pertussis has been applied in Iran since 1950. WHO suggests periodical evaluation of effectiveness of the triple diphtheria-tetanus-whole cell pertussis (DTwP) vaccine, worldwide. Objectives: To determine the immunogenicity of locally manufactured DTwP vaccine administered to preschool children in a number of health centers of Tehran in 2...

متن کامل

Preparation and Evaluation of Diphtheria Toxoid-Containing Microspheres

Preparation of chitosan (CS) microspheres as a novel drug delivery vehicle for intranasal immunization using high, medium and low CS molecular weight (MW) was investigated in this study. Diphtheria toxoid (DT) was used as a model antigen. The emulsion-solidification method was adopted for microencapsulation of DT.  In the first step, following the purification of semi-crude DT by the ion-exchan...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 20  شماره 

صفحات  -

تاریخ انتشار 2014